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MACROLIDES  
ANTIBIOTICS& ANTI INFECTIVES
 
     
  ERYTHROMYCIN  
     
 
It is acid labile therefore given as enteric coated tablets. Food delays its absorption. It does not cross blood brain barrier. It is excreted primarily in the bile in active from.
 
 
 
 
INDICATIONS : First choice drug for mycoplasma pneumonia, hegionnaine's pneumonia and whooping cough. It is used a second choice drug for Campylobacter enteritis, chancroid, chlamydia trachomatis and penicillin resistant staphylococcal infections. It is used as an alternative to penicillin in penicillin allergic patient for streptococcal pharyngitis, tonsillitis, mastoiditis and diphtherial, tetnus, syphilis and gonorrhoea infection.
 
 
 
 

SAFETY PROFILE :Generally safe but should be carefully given in patients who are taking non sedative antihistaminics.

 
 
 
 
ADVERSE EFFECTS :Mild to severe epigastric pain, anorexia, nausea, vomiting, diarrhoea, reversible hearing impairment (very high dose), rash and fever hepatitis with cholestatic jaundice.
 
 
 
 
DRUG INTERACTIONS : By inhibiting cytochrome P450, it increases the serum concentration of theophylline, oral anticoagulants, cyclosporine and methylprednisolone. It increases serum concentration of oral digoxin by increasing its bioavailabilty. Erythromycin if administered with terfenadine/ astemizole/ cisapride causes ventricular arrhythmias.
 
 
 
 
DOSAGE :Adult: 250-500mg 3-4 times daily.Gonorrhoea : 500mg 6 hrly for 6-7 days. Syphillis: 1gm 6 hrly for 10-15 days. Prophylaxis against streptococci: 250mg 12 hrly. Children : 30-50mg/kg/24 day in divided doses.
 
     
 
Brand
Company
Form
Pack
Strenth
Price
ALTHROCIN
ALEMBIC
1 Tab
10
250mg  
36.66
ALTHROCIN
ALEMBIC
2 Tab
10
500mg  
72.5
ALTHROCIN
ALEMBIC
1 Chew.
10
100mg  
16.28
ALTHROCIN
ALEMBIC
1 KT
10
125mg  
18.76
ALTHROCIN
ALEMBIC
Syp
60ml
125mg/5ml  
28.94
ALTHROCIN
ALEMBIC
Forte
30ml
250mg/ml  
23.81
ALTHROCIN
ALEMBIC
Drops
10ml
100mg/ml  
19.11
ARITOMYCIN
CADILA PHARMA
Tab
10
250mg  
 
CALTHROX
CADILA PHARMA
Tab
10
250mg  
19.58
CALTHROX
CADILA PHARMA
Susp
60ml
100mg/5ml  
22.57
E.E.S. 400
ABBOTT
Tab
10
400mg  
74.32
ELTOCIN
IPC A
Tab
10
250mg  
23.06
ELTOCIN
IPC A
Tab DS
10
500mg  
45.09
ELTOCIN
IPC A
DT
10
125mg  
11.97
ELTOCIN
IPC A
Syrup
30ml
125mg/5ml  
21.68
ELTOCIN ER
IPC A
ERTab
10
500mg  
45.09
ELUCIN
IND SWIFT
Tab
10
333mg  
43.24
ELUCIN
IND SWIFT
Susp
60ml
125mg/5ml  
26.34
EMTHROCIN
PIRAMAL H.C.
Susp
60ml
125mg/5ml  
24.99
EMTHROCIN
PIRAMAL H.C.
[Tab
10
250mg  
33.08
EMYCIN
THEMIS
Tab
10
250mg  
36.01
EMYCIN
THEMIS
DSyp
30ml
100mg/5ml  
9.41
EROATE
LUPIN
Tab
10
125mg  
15.95
EROATE
LUPIN
Tab
10
250mg  
26.05
EROATE
LUPIN
Tab
10
500mg  
50.4
EROATE
LUPIN
Syp
60ml
125mg/5ml  
27.03
EROCYN
BACTOLAC
Tab
10
125mg  
19.5
EROKID
ABBOTT
Tab
10
125mg  
26.4
ERYACNE
EMCURE
Gel
20g
4%  
37.5
ERYBEST
BLUE CROSS
Tab
10
250mg  
35.64
ERYBEST
BLUE CROSS
Tab P
10
125mg  
17.72
ERYCIN
CIPLA
DT
10
125mg  
16.3
ERYCIN
CIPLA
Tab
10
250mg  
28.24
ERYCIN
CIPLA
Tab
10
500mg  
55.64
ERYCIP
CIPLA
FC-Tab
10
250mg  
22.83
ERYSAFE
USV
Tab
10
250mg  
40.71
ERYTHROCIN
PHARMACIA
Tab
10
250mg  
32.58
ERYTHROCIN
PHARMACIA
Tab
10
500mg  
64.32
ERYTHROCIN
PHARMACIA
Susp
60ml
100mg/5ml  
25.53
ERYTHROKEM
ALKEM
Tab
10
250mg  
31.5
ESTORIM
TALENT LABS
KT
10
125mg  
23
ETOMIN
SUN
Tab
10
125mg  
15.03
ETOMIN
sun.
Tab
10
250mg  
28.91
ETOMIN
sun p
Tab
10
500mg  
57.13
ETOMIN
SUN PH
Susp
60ml
125mg/5ml  
24.68
INDERYTH
INDOCO
Susp
60ml
125mg/5ml  
26.3
RESTOMYCIN
ASTRA ZENECA
Tab
10
250mg  
29.64
 
     
 
     
 
     
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