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CORTICOSTEROIDS  
ENDOCRINE SYSTEM
 
     
  DEFLAZACORT  
     
 
Deflazacor is an oxazoiine derivative of prednisolone with anti-inflammatory and immunosuppressive activity.
 
 
 
 
INDICATIONS : Deflazacort used in situations where corticosteroid treatment is necessary like Rheumatoid arthritis. Juvenile chronic arthritis, asthma and other airway diseases. Deflazacort is not suitable for everyone and some people should never use it, other people should only use it with special care.
 
 
 
 
CONTRAINDICATIONS : Hypersensitivity, elderely. emotionally unstable condition, diabetes or a family H/o diabetes, gastritis or oesophagitis, hypothyroidism,kidney, liver or thromboembolic problems, ulcerative colitis. Patients receiving live virus immunisatton.
 
 
 
 

SAFETY PROFILE :Adrenal cortical atrophy develops during prolonged therapy and may persist for year after stopping treatment. withdraw of corticosteroids after prolonged therapy must therefore always be gradual to avoid acute adrenal insufficiency. caution required in cardiac disease or CHF (except in the presence of active rheumatic carditis), hypertension. glucocorticoids can cause salt and water retention and increased excretion of potassium. myasthenia gravis, renal insufficiency. psychotic tendency, epilepsy. previous corticosteroid-induced myopathy. ocular herpas simplex.

 
 
 
 
ADVERSE EFFECTS :Adrenal problems, appetite gain, diabetes, eye or eyesight problems, headaches, heart problems, irregular menstmal periods, nausea, oedema, pancreatitis, peptic uteers, acne, vertigo.
 
 
 
 
DRUG INTERACTIONS : It is recommended to increase the maintenance dose of deflazacort, if drugs, which are liver enzyme inducers are co-administered, e.g. rifampicin, rifabutin, carbamazepine, phenobarbitone. phenytoin, primidone and aminoglutethimide. For drug which inhibit liver enzymes, e.g. ketoconazole, it may be possible to reduce the maintenance dose of deflazacort.
 
 
 
 
DOSAGE :Adults: 6mg. Hepatic Impairment: Dose should be carefully monitored and adjusted to the minimum effective dose. Elderly: No special precautions other than those usually adopted in patients receiving glucocorticoid therapy are necessary. Children : Doses of deflazacort usually lie in the range 0.25 -1.5mg/kg/day. Susp. 5ml - 60ml per day
 
     
 
Brand
Company
Form
Pack
Strenth
Price
AB-CORT
AMERICAN BIOCARE
Tab
10
6mg  
87.9
ASTERIDE
DR. REDDY
Tab
6
6mg  
48.69
ASTERIDE
DR. REDDY
Tab
6
3Omg  
232.93
BIOZAC
BIOCHEMIX H.C.
Tab
10
3Omg  
335
CINCORT
CINEREA BIOTECH
Tab
6
6mg  
 
CORTIMAX
ZUVENTUS
Tab
6
1mg  
15
CORTIMAX
ZUVENTUS
Tab
6
6mg  
49
CORTIMAX
ZUVENTUS
Tab
6
24mg  
175
CORTIMAX
ZUVENTUS
Tab
6
24mg  
175
CORTISURE
ALEMBIC
Tab
10
1mg  
 
CORTISURE
ALEMBIC
Tab
11
6mg  
 
DECOTAZ
INTAS
Tab
10
6mg  
81
DECOTAZ
INTAS
Tab
10
30mg  
232
DEFCORT
MACLEODS
Susp
30ml
6mg/5ml  
48.27
DEFCORT
MACLEODS
Tab
10
1mg  
 
DEFCORT
MACLEODS
Tab
10
6mg  
 
DEFLACHEK
INDOCO
Tab .
6
30mg  
45
DEFLARIT
INTAS
Tab
6
6mg  
48
DEFLARIT
INTAS
Tab
6
30mg  
232
DEFLINK
FRANK MEOILINK
Tab
6
6mg  
 
DEFLOT
H & CARE INCORP.
Tab
10
6mg  
 
DEFLOT
H & CARE INCORP.
Tab
10
30mg  
 
DEFLOT
H & CARE INCORP
Susp
1
6mg/5ml  
 
DEFNALONE
LUPIN
Tab
10
1mg  
16.66
DEFNALONE
LUPIN
Tab
10
6mg  
81
DEFNALONE
LUPIN
Tab
10 .
24mg  
180
DEFNALONE
LUPIN
Tab
10
30mg  
232.93
DEFRUT
TRUMAC H.C.
Tab
10
6mg  
 
DEFZA
WALLACE
Tab
10
1mg  
 
DEFZONA
CADILA H.C.
Tab
10
1mg  
19
DEZOCORT
ZYDUS (A REME)
Tab
3
30mg  
115
DEZORT-6
MALODY H.C.
Tab
10
6mg  
 
DFT-6
ROSE LABS(HUMAN CARE)
Tab
10
6mg  
99
DFZ
IPCA
Tab
10
1mg  
15
DFZ
IPCA
Tab
10
30mg  
220
DIVLAZA
DIYA H.C.
Tab
6
6mg  
130
DZ CORT
SAMSON LAB
Tab
10
6mg  
 
EMPED
HUMAN CARE REME.
Tab
10
6mg  
7.5
FLAZLAR
STELLAR BIO -LABS
Tab
10
6mg  
80
FLOZAMIN
MINOVA LIFE SC.
Tab
6x5ml
6mg  
1080
FLOZAMIN
MINOVA LIFE SC.
Tab
6x10
6mg  
1080
FLOZAMIN
MINOVA LIFE SC.
Tab
6X20
6mg  
1080
FLOZAMIN
MINOVA LIFE SC.
Tab
6X20
6mg  
1080
MP NEXT
MEDIEZ PHARMA
Tab
10
6mg  
66
NURADEF-6
MEPFARMA
Tab
10
6mg  
 
PREDEN
EDEN H.C.
Tab
10
6mg  
79
TENFLAY
DR. REDDY
Tab
6
6mg  
1
TENFLAY
DR REDDY
Tab
6
30mg  
233
ZASA
PHARMACON H.C.
Tab
10
6mg  
 
 
     
 
     
 
     
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